AP4B1 Antibody

• Gene Name:

  Adaptor related protein complex 4 subunit beta 1

• Gene Aliases:

  Adaptor related protein complex 4 beta 1 subunit; Adaptor-related protein complex 4 subunit beta-1; AP-4 adaptor complex subunit beta; AP-4 complex subunit beta-1; beta 4 subunit of AP-4; Beta subunit of AP-4; BETA-4; beta4-adaptin; CPSQ5; spastic paraplegia 47; SPG47.

• Gene ID:

  10717

• Accession Number:

  NP_001240781

• Reactivity:

  Human

• Immunogen:

  Recombinant Human AP-4 complex subunit beta-1 protein (201-500AA)

• Target:

  Component of the adaptor protein complex 4 (AP-4) . Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways (PubMed:10066790, PubMed:10436028) . AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asymmetric localization of somatodendritic proteins in neurons. AP-4 is involved in the recognition and binding of tyrosine-based sorting signals found in the cytoplasmic part of cargos, but may also recognize other types of sorting signal (Probable) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  AP4B1

• Host or Source:

  Rabbit

• Protein Name:

  AP-4 complex subunit beta-1

• Gene Name URL:

  AP4B1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001253852