TRMT112 Antibody

• Gene Name:

  TRNA methyltransferase activator subunit 11-2

• Gene Aliases:

  HSPC152; HSPC170; hTrm112; multifunctional methyltransferase subunit TRM112-like protein; TRM112; TRM112-like protein; TRMT11-2; tRNA methyltransferase 112 homolog; tRNA methyltransferase 11-2 homolog; tRNA methyltransferase subunit 11-2.

• Gene ID:

  51504

• Accession Number:

  NP_001273011

• Reactivity:

  Human

• Immunogen:

  Recombinant Human tRNA methyltransferase 112 homolog protein (1-125AA)

• Target:

  Acts as an activator of both rRNA/tRNA and protein methyltransferases (PubMed:25851604) . Together with methyltransferase BUD23, methylates the N (7) position of a guanine in 18S rRNA (PubMed:25851604) . The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor (PubMed:18539146) . The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (PubMed:20308323) . Involved in the pre-rRNA processing steps leading to small-subunit rRNA production (PubMed:25851604) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  TRMT112

• Host or Source:

  Rabbit

• Protein Name:

  Multifunctional methyltransferase subunit TRM112-like protein

• Gene Name URL:

  TRMT112

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001286082