CLYBL Antibody

• Gene Name:

  Citramalyl-CoA lyase

• Gene Aliases:

  (3S) -malyl-CoA thioesterase; beta-methylmalate synthase; citramalyl-CoA lyase, mitochondrial; citrate lyase beta like; Citrate lyase subunit beta-like protein; citrate lyase subunit beta-like protein, mitochondrial; CLB; malate synthase.

• Gene ID:

  171425

• Accession Number:

  NP_996531

• Reactivity:

  Human|Mouse

• Immunogen:

  Recombinant Human Citrate lyase subunit beta-like protein, mitochondrial protein (23-340AA)

• Target:

  Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism (PubMed:29056341) . Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway (PubMed:29056341) . The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite (PubMed:29056341) . Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate (PubMed:24334609, PubMed:29056341) . Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate (PubMed:24334609, PubMed:29056341) . Also has very weak citramalate synthase activity in vitro (PubMed:24334609, PubMed:29056341) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunohistochemistry|Western blot

• Purification:

  Protein G Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  -20°C or -80°C

• Fragment:

  IgG

• NCBI Gene Symbol:

  CLYBL

• Host or Source:

  Rabbit

• Protein Name:

  Citramalyl-CoA lyase, mitochondrial

• Gene Name URL:

  CLYBL

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_206808