Products for Research Use Only
RegisterLogin

HSPA5 Antibody

CAT: 0247-OACA04084-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OACA04084-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Heat shock protein family A (Hsp70) member 5
Gene Aliases
78 kDa glucose-regulated protein; binding-immunoglobulin protein; BIP; endoplasmic reticulum chaperone BiP; endoplasmic reticulum lumenal Ca (2+) -binding protein grp78; epididymis secretory sperm binding protein Li 89n; glucose-regulated protein, 78kDa; GRP78; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) ; heat shock protein 70 family protein 5; heat shock protein family A member 5; HEL-S-89n; HSP70 family protein 5; immunoglobulin heavy chain-binding protein.
Gene ID
3309
Accession Number
NP_005338
Reactivity
Human
Immunogen
Recombinant Human Endoplasmic reticulum chaperone BiP protein (25-293AA)
Target
Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (PubMed:2294010, PubMed:23769672, PubMed:23990668, PubMed:28332555) . Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity) . Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (PubMed:1550958, PubMed:19538957) . In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1 (By similarity) . Accumulation of misfolded protein in the endoplasmic reticulum causes release of HSPA5/BiP from ERN1/IRE1, allowing homodimerization and subsequent activation of ERN1/IRE1 (By similarity) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
HSPA5
Host or Source
Rabbit
Protein Name
Endoplasmic reticulum chaperone BiP
Gene Name URL
HSPA5
Nucleotide Accession Number
NM_005347

Related Products

CatalogName
OPPA02589-5UGHSPA5 Protein
OPCD04021-50UGHSPA5 Recombinant Protein
OCOA12660-20UGHSPA5 Protein Lysate
OPCD04021-10UGHSPA5 Recombinant Protein
OPCD04021-200UGHSPA5 Recombinant Protein
OACA12735-100ULHSPA5 Recombinant Antibody [4H12] (OACA12735)
OKEH03933-96WHSPA5 ELISA Kit (Pig)
OPCA04230-20UGHSPA5 Recombinant Protein (Mouse)
OKCD02599-96WHSPA5 ELISA Kit (Mouse)
OPCA04230-100UGHSPA5 Recombinant Protein (Mouse)

Alternative Products

CatalogName
MBS7123020-01HSPA5 Antibody
49992Hspa5 Antibody

Popular Products