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BLOC1S1 Antibody

CAT: 0247-OACA02723-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0247-OACA02723-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Biogenesis of lysosomal organelles complex 1 subunit 1
Gene Aliases
Biogenesis of lysosome-related organelles complex 1 subunit 1; BLOC-1 subunit 1; BLOS1; BORCS1; GCN5 (general control of amino-acid synthesis, yeast, homolog) -like 1; GCN5 general control of amino-acid synthesis 5-like 1; GCN5L1; GCN5-like protein 1; MICoA; MTA1-interacting coactivator; Protein RT14; RT14.
Gene ID
2647
Accession Number
NP_001478
Reactivity
Human
Immunogen
Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 1 protein (1-153AA)
Target
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension (PubMed:17182842) . As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Western blot
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG
NCBI Gene Symbol
BLOC1S1
Host or Source
Rabbit
Protein Name
Biogenesis of lysosome-related organelles complex 1 subunit 1
Gene Name URL
BLOC1S1
Nucleotide Accession Number
NM_001487

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