S100B Antibody

CAT: 0247-OACA02448-50UGSize: 50 µgDry Ice: NoHazardous: No
CAT#:0247-OACA02448-50UGSize:50 µg
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CAS Number
9007-83-4
Gene Name
S100 calcium binding protein B
Gene Aliases
NEF; protein S100-B; S100; S100 calcium-binding protein B; S100 calcium-binding protein, beta (neural) ; S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100-B; S100beta.
Gene ID
6285
Accession Number
NP_006263
Reactivity
Human
Immunogen
Recombinant Human S100B protein
Target
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Monoclonal Antibody
Applications
Enzyme-linked immunosorbent assay
Purification
Protein G Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
-20°C or -80°C
Fragment
IgG1
Specificity
Specific for S100B native and denatured forms
NCBI Gene Symbol
S100B
Host or Source
Mouse
Protein Name
Protein S100-B
Gene Name URL
S100B
Nucleotide Accession Number
NM_006272

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