DUSP3 Polyclonal Antibody

CAT: 0247-OABB00714-100UGSize: 100 µg/VialDry Ice: NoHazardous: No
CAT#:0247-OABB00714-100UGSize:100 µg/Vial
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
CAS Number
9007-83-4
Gene Name
Signal transducer and activator of transcription 3
Gene Aliases
Acute-phase response factor; ADMIO; ADMIO1; APRF; DNA-binding protein APRF; HIES; signal transducer and activator of transcription 3.
Gene ID
6774
Swiss Prot
P04049
Reactivity
Human
Immunogen
A synthesized peptide derived from human Phospho-STAT3 (S727)
Clonality
Recombinant Monoclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Purification
Affinity Purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580, PubMed:23084476) . Once activated, recruits coactivators, such as NCOA1 or MED1, to the promoter region of the target gene (PubMed:17344214) . May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:12873986) . Binds to the interleukin-6 (IL-6) -responsive elements identified in the promoters of various acute-phase protein genes (PubMed:12359225) . Activated by IL31 through IL31RA (PubMed:15194700) . Acts as a regulator of inflammatory response by regulating differentiation of naive CD4 (+) T-cells into T-helper Th17 or regulatory T-cells (Treg) : deacetylation and oxidation of lysine residues by LOXL3, leads to disrupt STAT3 dimerization and inhibit its transcription activity (PubMed:28065600) . Involved in cell cycle regulation by inducing the expression of key genes for the progression from G1 to S phase, such as CCND1 (PubMed:17344214) . Mediates the effects of LEP on melanocortin production, body energy homeostasis and lactation (By similarity) . May play an apoptotic role by transctivating BIRC5 expression under LEP activation (PubMed:18242580) . Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity (PubMed:23084476) . Plays a crucial role in basal beta cell functions, such as regulation of insulin secretion (By similarity) .
Format
Liquid
Reconstitution
-20°C or -80°C
NCBI Gene Symbol
STAT3
Protein Name
Signal transducer and activator of transcription 3
Gene Name URL
STAT3

Related Products

CatalogName
OACD00390-100ULDUSP3 Antibody
OACD00390-200ULDUSP3 Antibody
OACD03128-100ULDUSP3 Antibody
OAGA00742-100ULDUSP3 antibody
OAAF08075-100UGDUSP3 Antibody
OACD00390-1MLDUSP3 Antibody
OACD03128-1MLDUSP3 Antibody
OAAB17610-400ULDUSP3 Antibody - C-terminal region
OAAF08075-100UG-BiotinDUSP3 Antibody : Biotin (OAAF08075-Biotin)
OAAF08075-100UG-HRPDUSP3 Antibody : HRP (OAAF08075-HRP)

Alternative Products

CatalogName
MBS2564702-01DUSP3 Polyclonal Antibody
BS74732DUSP3 polyclonal antibody
APRab01377-01DUSP3 Rabbit Polyclonal Antibody
PHE81801Anti-DUSP3 Polyclonal Antibody
NBP2-98873-50ulRabbit Polyclonal VHR/DUSP3 Antibody
bs-6246R-Cy5DUSP3 Polyclonal Antibody, Cy5 Conjugated
bs-6246R-Cy7DUSP3 Polyclonal Antibody, Cy7 Conjugated
bs-6246R-PEDUSP3 Polyclonal Antibody, PE Conjugated
PA1125-.05Anti-DUSP3 Rabbit Polyclonal Antibody
MBS8594307-01DUSP3 Antibody

Popular Products