FBXO2 Antibody

CAT: 0247-OAAN03900-200ULSize: 200 µLDry Ice: NoHazardous: No
CAT#:0247-OAAN03900-200ULSize:200 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
F-box protein 2
Gene Aliases
FBG1, FBX2, Fbs1, OCP1, NFB42
Gene ID
26232
Swiss Prot
Q9UK22
Accession Number
NP_036300.2
Reactivity
Mouse, Rat
Immunogen
Recombinant Protein
Target
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purification
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
33 kDa
Fragment
IgG
NCBI Gene Symbol
FBXO2
Host or Source
Rabbit
Protein Name
Autophagy-related protein 2 homolog A
Gene Name URL
FBXO2
Nucleotide Accession Number
NM_012168.5

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