POLR2G Antibody

• Gene Name:

  RNA polymerase II subunit G

• Gene Aliases:

  DNA directed RNA polymerase II 19 kda polypeptide; DNA-directed RNA polymerase II 19 kDa polypeptide; DNA-directed RNA polymerase II subunit G; DNA-directed RNA polymerase II subunit RPB7; hRPB19; hsRPB7; polymerase (RNA) II (DNA directed) polypeptide G; polymerase (RNA) II subunit G; RNA polymerase II 19 kDa subunit; RNA polymerase II seventh subunit; RNA polymerase II subunit B7; RPB19; RPB7.

• Gene ID:

  5436

• Swiss Prot:

  P62487

• Accession Number:

  NP_002687.1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  POLR2G

• Target:

  DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity) . Binds RNA.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Western blot

• Purification:

  Affinity purification

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Reconstitution:

  Store at +4C. For long term storage, aliquote and store at -20C. Avoid freeze/thaw cycles.

• Molecular Weight:

  19kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  POLR2G

• Host or Source:

  Rabbit

• Protein Name:

  DNA-directed RNA polymerase II subunit RPB7

• Gene Name URL:

  POLR2G

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_002696.2