SOCS4 Antibody

• Gene Name:

  Suppressor of cytokine signaling 4

• Gene Aliases:

  SH2 domain containing SOCS box protein; SOCS-4; SOCS7; SOCS-7; suppressor of cytokine signaling 4; suppressor of cytokine signaling 7.

• Gene ID:

  122809

• Swiss Prot:

  Q8WXH5

• Accession Number:

  NP_543143.1

• Reactivity:

  Human, Mouse

• Immunogen:

  SOCS4

• Target:

  SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  Western blot

• Purification:

  Affinity purified against immunogen

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Format:

  Liquid

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Reconstitution:

  Store at -20C. Avoid repeated freeze/thaw cycles.

• Molecular Weight:

  51kDa

• Fragment:

  IgG

• NCBI Gene Symbol:

  SOCS4

• Host or Source:

  Rabbit

• Protein Name:

  Suppressor of cytokine signaling 4

• Gene Name URL:

  SOCS4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_080867.2