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SOCS4 Antibody

CAT: 0223-57-808Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-808Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
122809
Swiss Prot
Q8WXH5
Accession Number
Q8WXH5
Host
Rabbit
Reactivity
Human
Immunogen
This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 224-253 amino acids from the Central region of human SOCS4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SOCS4
NCBI Official Name
Suppressor of cytokine signaling 4
NCBI Organism
Homo sapiens
Background Reference 01
Hu, G., et al. J. Infect. Dis. 202 (1) :125-135 (2010)
Background Reference 02
Han, S., et al. Hum. Immunol. 71 (7) :727-730 (2010)
Background Reference 03
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19 (5) :1356-1361 (2010)
Background Reference 04
Sasi, W., et al. BMC Cancer 10, 178 (2010) :
Other Product Names
Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7
Tested Applications
WB
Protein ID
20178106
Physical Properties
Liquid

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