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CARD8 Antibody

CAT: 0247-OAAN00080-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAN00080-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Caspase recruitment domain family member 8
Gene Aliases
NDPP, DACAR, DAKAR, NDPP1, TUCAN, CARDINAL
Gene ID
22900
Swiss Prot
Q9Y2G2
Accession Number
NP_001171829.1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human CARD8
Target
The protein encoded by this gene belongs to the caspase recruitment domain (CARD) -containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB) . This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity purified against immunogen
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Reconstitution
Store at -20C. Avoid repeated freeze/thaw cycles.
Molecular Weight
49 kDa
Fragment
IgG
NCBI Gene Symbol
CARD8
Host or Source
Rabbit
Protein Name
Caspase recruitment domain-containing protein 8
Gene Name URL
CARD8
Nucleotide Accession Number
NM_001184900.1

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