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UPB1 Antibody

CAT: 0247-OAAL00699-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00699-100UGSize:100 µg
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CAS Number
9007-83-4
Gene Name
Beta-ureidopropionase 1
Gene Aliases
Beta-alanine synthase; beta-ureidopropionase; BUP1; n-carbamoyl-beta-alanine amidohydrolase; ureidopropionase, beta.
Gene ID
51733
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_057411.1
Reactivity
Human, Mouse
Immunogen
UPB1 (NP_057411.1, 285 a.a. ~ 384 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq
Clonality
Monoclonal
Clone
3F12
Type
Monoclonal Antibody
Sequence
AINRVGTEHFPNEFTSGDGKKAHQDFGYFYGSSYVAAPDSSRTPGLSRSRDGLLVAKLDLNLCQQVNDVWNFKMTGRYEMYARELAEAVKSNYSPTIVKE
Applications
Enzyme-linked immunosorbent assay|Immunohistochemistry-Paraffin|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG1 Kappa
NCBI Gene Symbol
UPB1
Host or Source
Mouse
Protein Name
Beta-ureidopropionase [Homo sapiens]|Homo sapiens beta-ureidopropionase 1 (UPB1), mRNA
Gene Name URL
UPB1
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_016327