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CHMP2B Antibody

CAT: 0247-OAAL00622-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00622-100UGSize:100 µg
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CAS Number
9007-83-4
Gene Name
Charged multivesicular body protein 2B
Gene Aliases
ALS17; charged multivesicular body protein 2b; CHMP2.5; chromatin modifying protein 2B; DMT1; FTDALS7; vacuolar protein-sorting-associated protein 2-2; VPS2 homolog B; VPS2-2; VPS2B.
Gene ID
25978
Accession Number
https://www.ncbi.nlm.nih.gov/protein/AAH01553.1
Reactivity
Human, Mouse
Immunogen
CHMP2B (AAH01553.1, 1 a.a. ~ 213 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. [provided by RefSeq
Clonality
Monoclonal
Clone
2H6-1E6
Type
Monoclonal Antibody
Sequence
MASLFKKKTVDDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVLAKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKTLQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKAPSAARSLPSASTSKATISDEEIERQLKALGVD
Applications
Enzyme-linked immunosorbent assay
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG1 kappa
NCBI Gene Symbol
CHMP2B
Host or Source
Mouse
Protein Name
Chromatin modifying protein 2B [Homo sapiens]|Homo sapiens chromatin modifying protein 2B, mRNA (cDNA clone MGC:5027 IMAGE:3460712), complete cds
Gene Name URL
CHMP2B
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/BC001553.1

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