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ACTL6A Antibody

CAT: 0247-OAAL00004-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAL00004-100UGSize:100 µg
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CAS Number
9007-83-4
Gene Name
Actin like 6A
Gene Aliases
53 kDa BRG1-associated factor A; actin-like protein 6A; actin-related protein 4; actin-related protein Baf53a; ACTL6; Arp4; arpNbeta; ARPN-BETA; BAF complex 53 kDa subunit; BAF53; BAF53A; BRG1-associated factor 53A; hArpN beta; INO80 complex subunit K; INO80K; SMARCN1.
Gene ID
86
Accession Number
https://www.ncbi.nlm.nih.gov/protein/NP_817126
Reactivity
Human, Mouse
Immunogen
ACTL6A (NP_817126, 1 a.a. ~ 80 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq
Clonality
Monoclonal
Clone
3C4
Type
Monoclonal Antibody
Sequence
MVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVPRENMEAISPLKNGMVEDWDSFQAILDHTYKMHVKSEASLHPVLM
Applications
Enzyme-linked immunosorbent assay|Western blot
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
Liquid
Reconstitution
Store at -20C or lower. Aliquot to avoid repeated freezing and thawing.
Fragment
IgG1 Kappa
NCBI Gene Symbol
ACTL6A
Host or Source
Mouse
Protein Name
Actin-like protein 6A isoform 2 [Homo sapiens]|Homo sapiens actin like 6A (ACTL6A), transcript variant 2, mRNA
Gene Name URL
ACTL6A
Nucleotide Accession Number
https://www.ncbi.nlm.nih.gov/nuccore/NM_177989

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