Products for Research Use Only
RegisterLogin

PRKAG2 Antibody

CAT: 0247-OAAJ11729-100ULSize: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAJ11729-100ULSize:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Aliases
AAKG, CMH6, WPWS, AAKG2, H91620p
Gene ID
51422
Swiss Prot
Q9UGJ0
Accession Number
NP_001035723
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human AMPKgamma2
Target
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
Immunogen affinity chromatography
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid
Reconstitution
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Molecular Weight
65 kDa
NCBI Gene Symbol
PRKAG2
Host or Source
Rabbit
Protein Name
5'-AMP-activated protein kinase subunit gamma-2
Gene Name URL
PRKAG2
Nucleotide Accession Number
NM_001040633

Related Products

CatalogName
OPCD06404-200UGPRKAG2 Recombinant Protein
OPCD06404-10UGPRKAG2 Recombinant Protein
OCOA02277-20UGPRKAG2 Protein Lysate
OPCD06404-50UGPRKAG2 Recombinant Protein
OCOA15642-20UGPRKAG2 Protein Lysate
OPCA04354-20UGPRKAG2 Recombinant Protein (Human)
OPCA04354-1MGPRKAG2 Recombinant Protein (Human)
OPCA04354-100UGPRKAG2 Recombinant Protein (Human)
OAAB19828-100ULPRKAG1 Antibody
OACA07603-100ULPRKAB2 Antibody

Alternative Products

CatalogName
70R-32185PRKAG2 antibody
MBS8568972-01PRKAG2 Polyclonal Antibody
CSB-CL887021HU1PRKAG2

Popular Products