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UMOD Antibody

CAT: 0247-OAAJ07166-100ULSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0247-OAAJ07166-100ULSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
THP, FJHN, HNFJ, THGP, HNFJ1, MCKD2, ADTKD1, ADMCKD2
Gene ID
7369
Swiss Prot
P07911
Accession Number
NP_001008390
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human UMOD, corresponding to a region within C-terminal amino acids.
Target
Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable) . May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB, IHC, P-ELISA
Purification
Purified by peptide affinity chromatography.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/mL
Format
Liquid// PBS (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution
Store at -20° C. Stable for 12 months from date of receipt.
Molecular Weight
70 kDa
Specificity
UMOD Antibody detects endogenous levels of total UMOD.
NCBI Gene Symbol
UMOD
Host or Source
Rabbit
Protein Name
Uromodulin
Gene Name URL
UMOD
Nucleotide Accession Number
NM_001008389