Products for Research Use Only
RegisterLogin

ENG Antibody

CAT: 0247-OAAF08251-50ULSize: 0.05 mLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF08251-50ULSize:0.05 mL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Endoglin
Gene Aliases
CD105 antigen; END; endoglin; HHT1; ORW1.
Gene ID
2022
Swiss Prot
P17813
Accession Number
NP_000109.1
Reactivity
Human
Immunogen
Synthetic peptide.
Target
Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529) . Required for normal structure and integrity of adult vasculature (PubMed:7894484) . Regulates the migration of vascular endothelial cells (PubMed:17540773) . Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity) . May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity) . May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors (PubMed:1692830) . Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade that ultimately leads to the activation of SMAD transcription factors (PubMed:8370410, PubMed:21737454, PubMed:22347366, PubMed:23300529) . Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGFB1 signaling through SMAD3 (PubMed:21737454, PubMed:22347366, PubMed:23300529) .
Clonality
Monoclonal
Clone
ABT-CD105
Type
Monoclonal Antibody
Applications
Immunohistochemistry
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Format
PBS, pH7.2, 0.03% Proclin 300, 50% glycerol
Reconstitution
-20°C
Molecular Weight
70 kDa
Fragment
IgG
Specificity
Anti-CD105 (Endoglin) [ABT-CD105] detects endogenous levels of total CD105 (Endoglin) protein.
NCBI Gene Symbol
ENG
Host or Source
Mouse
Protein Name
Endoglin
Gene Name URL
ENG
Nucleotide Accession Number
NM_000118.3

Related Products

CatalogName
OAOA21637-100UGENG Capture Antibody
OAOA22095-50UGENG Detection Antibody
OAOA21634-100UGENG Capture Antibody
OAOA21636-100UGENG Capture Antibody
OAOA21635-100UGENG Capture Antibody
OAOA22094-50UGENG Detection Antibody
OAOA22093-50UGENG Detection Antibody
ARP33068_T100Anti-ENG
OCOA17552-20UGENG Protein Lysate
OCOA18365-20UGENG Protein Lysate

Alternative Products

CatalogName
MBS8529199-01H2B Antibody Antibody
MBS8513599-01CD11b Antibody Antibody
DF8746-01ASAP1 antibody Antibody
MBS850197-01Antibody to IGFBP2 Antibody
E36403ZNF98 Antibody Antibody
GWB-250026Lck antibody Antibody
E8M1007-4HSP60 Antibody Antibody
MBS9403836-01SZT2 Antibody Antibody
LSMab09882anti-Antibody^Polyclonal antibody control antibody
GWB-5C6547MAD1L1 antibody [9B10] Antibody

Popular Products