Anti-ENG

• Gene Name:

  Endoglin

• Gene Aliases:

  END, HHT1, ORW1

• Gene ID:

  2022

• Swiss Prot:

  P17813

• Accession Number:

  NP_000109

• Reactivity:

  Human, Mouse, Rat, Guinea Pig

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human ENG

• Target:

  Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.

• Partner Proteins:

  ENG; TGFBR2; TGFBR1; TGFB3; TGFB1; ACVRL1; TUFM; TCTEX1D4; TGFBR3; TGFB2; INHBA; BMP7; BMP2; ACVR2A; ACVR1; ACVR2B

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ

• Applications:

  IHC, WB

• Purification:

  Protein A purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1.0 mg/ml

• Homology:

  Guinea Pig: 91%; Human: 100%; Mouse: 91%; Rat: 91%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  68kDa

• Protein Length:

  625

• NCBI Gene Symbol:

  ENG

• Host or Source:

  Rabbit

• Protein Name:

  Endoglin

• Gene Name URL:

  ENG

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_000118