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MCM6 Antibody

CAT: 0247-OAAF08077-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF08077-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Minichromosome maintenance complex component 6
Gene Aliases
DNA replication licensing factor MCM6; MCG40308; MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) ; minichromosome maintenance deficient (mis5, S. pombe) 6; Mis5; P105MCM.
Gene ID
4175
Swiss Prot
Q14566
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human MCM6. AA range:331-380
Target
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
VKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTT
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid// PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Reconstitution
Store at -20° C for 1 year.
Molecular Weight
92 kDa
Specificity
MCM6 Antibody detects endogenous levels of MCM6 protein.
NCBI Gene Symbol
MCM6
Host or Source
Rabbit
Protein Name
DNA replication licensing factor MCM6
Gene Name URL
MCM6

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