Products for Research Use Only
RegisterLogin

FZD2 Antibody

CAT: 0247-OAAF04815-100UGSize: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0247-OAAF04815-100UGSize:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
9007-83-4
Gene Name
Frizzled class receptor 2
Gene Aliases
Frizzled 2, seven transmembrane spanning receptor; frizzled family receptor 2; frizzled homolog 2; frizzled-2; fz-2; Fz2; fzE2; hFz2; OMOD2.
Gene ID
2535
Swiss Prot
Q14332
Accession Number
NP_001457.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human FZD2.
Target
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
63 kDa
Notes
Formerly GWB-ASF219
Specificity
FZD2 antibody detects endogenous levels of total FZD2 protein.
NCBI Gene Symbol
FZD2
Host or Source
Rabbit
Protein Name
Frizzled-2
Gene Name URL
FZD2

Related Products

CatalogName
AAP41236-100UGFZD2 Peptide - N-terminal region (AAP41236)
OACA10109-50UGFZD8 Antibody
OACA09122-100ULFZD3 Antibody
OACA09122-50ULFZD3 Antibody
OACA09123-100ULFZD3 Antibody
OAAJ05699-100ULFZD9 Antibody
OALA00933-50UGFZD9 Antibody
OAEB02095-100UGFZD7 Antibody
OAAL00381-100UGFZD3 Antibody
OAAJ05804-100ULFZD1 Antibody

Alternative Products

CatalogName
GTR18123675FZD2 Antibody

Popular Products