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TACC3 Antibody

CAT: 0247-OAAF04493-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF04493-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Transforming acidic coiled-coil containing protein 3
Gene Aliases
ERIC1; ERIC-1; maskin; Tacc4; transforming acidic coiled-coil-containing protein 3.
Gene ID
10460
Swiss Prot
Q9Y6A5
Accession Number
NP_006333.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TACC3.
Target
Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity) . Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825) . May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Homology
Human; Mouse
Format
Liquid
Reconstitution
-20°C
Molecular Weight
90 kDa
Notes
Formerly GWB-ASF118
Specificity
TACC3 antibody detects endogenous levels of total TACC3 protein.
NCBI Gene Symbol
TACC3
Host or Source
Rabbit
Protein Name
Transforming acidic coiled-coil-containing protein 3
Gene Name URL
TACC3

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