HCN2 Antibody

• Gene Name:

  Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

• Gene Aliases:

  BCNG2; BCNG-2; brain cyclic nucleotide-gated channel 2; EIG17; FEB2; GEFSP11; HAC-1; hyperpolarization activated cyclic nucleotide gated potassium channel 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2.

• Gene ID:

  610

• Swiss Prot:

  Q9UL51

• Accession Number:

  NP_001185.3

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human HCN2.

• Target:

  Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih) . Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity) .

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Dilution:

  The optimal working dilution should be determined by the end user.

• Format:

  Liquid

• Reconstitution:

  -20°C

• Molecular Weight:

  96 kDa

• Notes:

  Formerly GWB-ASE858

• Specificity:

  HCN2 antibody detects endogenous levels of total HCN2 protein.

• NCBI Gene Symbol:

  HCN2

• Host or Source:

  Rabbit

• Protein Name:

  Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

• Gene Name URL:

  HCN2

• CAS Number:

  9007-83-4