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MARCH4 Antibody

CAT: 0247-OAAF03612-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF03612-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Membrane associated ring-CH-type finger 4
Gene Aliases
E3 ubiquitin-protein ligase MARCH4; E3 ubiquitin-protein ligase MARCHF4; MARCH4; MARCH-IV; membrane associated ring finger 4; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; membrane-associated RING finger protein 4; membrane-associated RING-CH protein IV; RING finger protein 174; RING-type E3 ubiquitin transferase MARCH4; RING-type E3 ubiquitin transferase MARCHF4; RNF174.
Gene ID
57574
Swiss Prot
Q9P2E8
Accession Number
NP_065865.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MARCH4.
Target
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
45 kDa
Notes
Formerly GWB-ASE558
Specificity
MARCH4 antibody detects endogenous levels of total MARCH4 protein.
NCBI Gene Symbol
MARCHF4
Host or Source
Rabbit
Protein Name
E3 ubiquitin-protein ligase MARCH4
Gene Name URL
MARCHF4

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