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CMTM4 Antibody

CAT: 0247-OAAF03500-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF03500-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
CKLF like MARVEL transmembrane domain containing 4
Gene Aliases
Chemokine-like factor super family 4; chemokine-like factor superfamily member 4; CKLF-like MARVEL transmembrane domain-containing protein 4; CKLFSF4.
Gene ID
146223
Swiss Prot
Q8IZR5
Accession Number
NP_848933.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CKLF4.
Target
Acts as a backup for CMTM6 to regulate plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. May protect PD-L1/CD274 from being polyubiquitinated and targeted for degradation.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution
-20°C
Molecular Weight
25 kDa
Fragment
IgG
Specificity
CKLF4 Antibody detects endogenous levels of CKLF4.
NCBI Gene Symbol
CMTM4
Host or Source
Rabbit
Protein Name
CKLF-like MARVEL transmembrane domain-containing protein 4
Gene Name URL
CMTM4

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