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NRAS Antibody

CAT: 0247-OAAF01913-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF01913-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
HRas proto-oncogene, GTPase|KRAS proto-oncogene, GTPase|NRAS proto-oncogene, GTPase
Gene Aliases
ALPS4; C-BAS/HAS; cellular c-Ki-ras2 proto-oncogene; cellular transforming proto-oncogene; CFC2; C-HA-RAS1; c-has/bas p21 protein; C-H-RAS; c-Ki-ras; c-Ki-ras2; c-Kirsten-ras protein; C-K-RAS; 'C-K-RAS; CMNS; CTLO; GTP- and GDP-binding peptide B; GTPase HRas; GTPase KRas; GTPase NRas; HAMSV; Ha-Ras; Ha-Ras1 proto-oncoprotein; Harvey rat sarcoma viral oncogene homolog; Harvey rat sarcoma viral oncoprotein; H-Ras-1; HRAS1; H-RASIDX; KI-RAS; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral proto-oncogene; K-Ras; K-Ras 2; K-ras p21 protein; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NCMS; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; N-ras; N-ras protein part 4; NRAS1; NS; NS3; NS6; OES; oncogene KRAS2; p19 H-RasIDX protein; p21ras; PR310 c-K-ras oncogene; RALD; Ras family small GTP binding protein H-Ras; RASH1; RASK2; transformation gene: oncogene HAMSV; transforming protein N-Ras; transforming protein p21; v-Ha-ras Harvey rat sarcoma viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-ras neuroblastoma RAS viral oncogene homolog.
Gene ID
3265|3845|4893
Swiss Prot
P01111|P01112|P01116
Accession Number
NP_004976.2
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RASH/RASK.
Target
Involved in the activation of Ras protein signal transduction (PubMed:22821884) . Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:12740440, PubMed:14500341, PubMed:9020151) .|Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621) . Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838) . Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306) .|Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
21 kDa
Notes
Formerly GWB-ASD183
Specificity
RASH/RASK/RASN antibody detects endogenous levels of total RASH/RASK/RASN protein.
NCBI Gene Symbol
HRAS|KRAS|NRAS
Host or Source
Rabbit
Protein Name
GTPase HRas|GTPase KRas|GTPase NRas
Gene Name URL
HRAS|KRAS|NRAS

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