DUSP1 Antibody

• Gene Name:

  Dual specificity phosphatase 1|dual specificity phosphatase 4

• Gene Aliases:

  CL 100; CL100; dual specificity protein phosphatase 1; dual specificity protein phosphatase 4; dual specificity protein phosphatase hVH1; dual specificity protein phosphatase hVH2; HVH1; HVH2; MAP kinase phosphatase 1; MAP kinase phosphatase 2; mitogen-activated protein kinase phosphatase 1; mitogen-activated protein kinase phosphatase 2; MKP1; MKP-1; MKP2; MKP-2; protein-tyrosine phosphatase CL100; PTPN10; serine/threonine specific protein phosphatase; TYP; VH1 homologous phosphatase 2.

• Gene ID:

  1843|1846

• Swiss Prot:

  P28562|Q13115

• Accession Number:

  NP_001385.1

• Reactivity:

  Human|Mouse|Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human MKP-1/2.

• Target:

  Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and 'Tyr-185', regulating its activity during the meiotic cell cycle.|Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Applications:

  Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

• Purification:

  The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  1 mg/ml

• Dilution:

  The optimal working dilution should be determined by the end user.

• Format:

  Liquid// PBS (without Mg2+ and Ca2+) (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol2+2+

• Reconstitution:

  -20°C

• Molecular Weight:

  39 kDa

• Notes:

  Formerly GWB-ASC979

• Specificity:

  MKP-1/2 (Ab-296/318) antibody detects endogenous levels of total MKP-1/2 protein.

• NCBI Gene Symbol:

  DUSP1|DUSP4

• Host or Source:

  Rabbit

• Protein Name:

  Dual specificity protein phosphatase 1|Dual specificity protein phosphatase 4

• Gene Name URL:

  DUSP1|DUSP4

• CAS Number:

  9007-83-4