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EIF4B Antibody (Phospho-Ser422)

CAT: 0247-OAAF00124-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF00124-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Eukaryotic translation initiation factor 4B|Janus kinase 1
Gene Aliases
AIIDE; EIF-4B; eukaryotic translation initiation factor 4B; JAK1A; JAK1B; JTK3; PRO1843; tyrosine-protein kinase JAK1.
Gene ID
1975|3716
Swiss Prot
P23588
Accession Number
NP_001408.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human eIF4B around the phosphorylation site of Ser422.
Target
Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
69 kDa
Notes
Formerly GWB-ASB263
Specificity
EIF4B (Phospho-Ser422) antibody detects endogenous levels of eIF4B only when phosphorylated at serine 422.
NCBI Gene Symbol
EIF4B|JAK1
Host or Source
Rabbit
Protein Name
Eukaryotic translation initiation factor 4B
Gene Name URL
EIF4B|JAK1

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