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SYT1 Antibody (Phospho-Thr202)

CAT: 0247-OAAF00022-100UGSize: 100 µgDry Ice: NoHazardous: No
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CAT#:0247-OAAF00022-100UGSize:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Name
Synaptotagmin 1|synaptotagmin 2
Gene Aliases
BAGOS; CMS7; CMS7A; CMS7B; MYSPC; P65; SVP65; synaptotagmin I; synaptotagmin II; synaptotagmin-1; synaptotagmin-2; SYT; sytI; SytII.
Gene ID
127833|6857
Swiss Prot
P21579|Q8N9I0
Accession Number
NP_001129277.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Synaptotagmin around the phosphorylation site of Thr202.
Target
Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity) . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .|May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca (2+) -dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca (2+) -independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
47 kDa
Notes
Formerly GWB-ASB032
Specificity
Synaptotagmin (phospho-Thr202) antibody detects endogenous levels of Synaptotagmin only when phosphorylated at threonine 202.
NCBI Gene Symbol
SYT1|SYT2
Host or Source
Rabbit
Protein Name
Synaptotagmin-1|Synaptotagmin-2
Gene Name URL
SYT1|SYT2

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