CCND1 Antibody

• Gene Name:

  G1/S-specific cyclin-D1

• Gene Aliases:

  BCL1, PRAD1, U21B31, D11S287E

• Gene ID:

  595

• Swiss Prot:

  P24385

• Accession Number:

  NP_444284.1

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant human cyclin D1 protein.

• Target:

  D-type cyclins (cyclins D1, D2, and D3) are regarded as essential links between cell environment and the core cell cycle machinery. CyclinD1 (CCND1), also known as BCL1. Expression of cyclin D1, but not of cyclins A and E, was induced by transfection of the RB gene into RB-deficient tumor cells. CCND1 gene to 11q13. cyclin D1 gene can function as an oncogene. Cyclin D1 expression is regulated by the retinoblastoma protein.

• Clonality:

  Monoclonal

• Clone:

  CY-D1

• Type:

  Monoclonal Antibody

• Applications:

  WB, IHC, IP, ICC

• Purification:

  Purified by the goat anti-mouse IgG Affinity chromatography.

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Buffer:

  1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

• Reconstitution:

  At -20C for one year. After reconstitution, at 4C for one month. It can also be aliquotted and stored frozen at -20C for longer time.

• Fragment:

  IgG2a

• NCBI Gene Symbol:

  CCND1

• Host or Source:

  Mouse

• Protein Name:

  G1/S-specific cyclin-D1

• Gene Name URL:

  CCND1

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_053056.2