PDE1A Antibody - N-terminal region

• Gene Name:

  Phosphodiesterase 1A

• Gene Aliases:

  HCAM1, HCAM-1, HSPDE1A, CAM-PDE 1A, CAM-PDE-1A

• Gene ID:

  5136

• Swiss Prot:

  P54750

• Accession Number:

  NP_001003683.1

• Reactivity:

  Human, Mouse

• Immunogen:

  This PDE1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-57 amino acids from human PDE1A.

• Target:

  Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) .[supplied by OMIM, Oct 2009]

• Clonality:

  Polyclonal

• Clone:

  RB53388

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Protein A column purification, followed by peptide affinity purification

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  500 ug/mL

• Homology:

  Human, Mouse

• Format:

  Liquid

• Reconstitution:

  Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  61 kDa

• Fragment:

  Rabbit Ig

• NCBI Gene Symbol:

  PDE1A

• Host or Source:

  Rabbit

• Gene Name URL:

  PDE1A

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_001003683.2