TRAF4 Antibody - middle region

• Gene Name:

  TNF receptor-associated factor 4

• Gene Aliases:

  CART1, MLN62, RNF83

• Gene ID:

  9618

• Swiss Prot:

  Q9BUZ4

• Accession Number:

  NP_004286

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human TRAF4

• Target:

  TRAF4 is a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. It has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P) H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK.This gene encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD (P) H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• Partner Proteins:

  HOMEZ; BYSL; REXO1L6P; PKD1P1; KANSL1; BCL6B; UBL4B; KRT40; FBXL18; BANP; SPDL1; ALKBH4; WBP11; ZNF581; ISYNA1; TBC1D7; GORASP2; EXOC7; BAHD1; WWP2; WWP1; MRPL28; NOS1AP; TRAF4; UBL4A; ZNF3; SUMO1; UBC; TYK2; TP53BP2; QARS; KRT31; ARNT2; TRAF2; USP15; TGF

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  LEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFL

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  53kDa

• Protein Length:

  470

• NCBI Gene Symbol:

  TRAF4

• Host or Source:

  Rabbit

• Protein Name:

  TNF receptor-associated factor 4

• Gene Name URL:

  TRAF4

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_004295