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Tirofiban (Standard)

CAT: 0804-HY-17369BR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17369BR-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tirofiban (Standard) is the analytical standard of Tirofiban. This product is intended for research and analytical applications. Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area[1][2][3].
CAS Number
144494-65-5
Product Name Alternative
L700462 (Standard) ; MK383 (Standard)
UNSPSC
12352005
Target
Integrin; Reference Standards
Type
Reference Standards
Related Pathways
Cytoskeleton; Others
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tirofiban-standard.html
Smiles
O=S(N[C@H](C(O)=O)CC1=CC=C(OCCCCC2CCNCC2)C=C1)(CCCC)=O
Molecular Formula
C22H36N2O5S
Molecular Weight
440.60
References & Citations
[1]Giordano A, et al. Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells. Vascul Pharmacol. 2014 May-Jun;61 (2-3) :63-71.|[2]Liu X, et al. Effects of tirofiban on the reperfusion-related no-reflow in rats with acute myocardial infarction. J Geriatr Cardiol. 2013 Mar;10 (1) :52-8.|[3]Yates YJ, et al. The effect of tirofiban on microvascular thrombosis: crush model. Plast Reconstr Surg. 2005 Jul;116 (1) :205-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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