Products for Research Use Only
RegisterLogin

Tirofiban

CAT: 0804-HY-17369B-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-17369B-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Tirofiban (L700462) is a selective and reversible platelet integrin receptor (Gp IIb/IIIa) antagonist that inhibits fibrinogen binding to this receptor and has antithrombotic activity. Tirofiban induces proliferation and migration on endothelial cell by inducing production of VEGF. Tirofiban can significantly reduces myocardial no-reflow and ischemia-reperfusion injury by alleviating myocardial microvascular structural and endothelial dysfunction in the ischemic area[1][2][3].
CAS Number
144494-65-5
Product Name Alternative
L700462; MK383
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Integrin
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tirofiban.html
Purity
99.95
Solubility
DMSO : < 1 mg/mL (ultrasonic; warming) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=S(N[C@H](C(O)=O)CC1=CC=C(OCCCCC2CCNCC2)C=C1)(CCCC)=O
Molecular Formula
C22H36N2O5S
Molecular Weight
440.60
Precautions
H315, H319, H335
References & Citations
[1]Giordano A, et al. Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells. Vascul Pharmacol. 2014 May-Jun;61 (2-3) :63-71.|[2]Liu X, et al. Effects of tirofiban on the reperfusion-related no-reflow in rats with acute myocardial infarction. J Geriatr Cardiol. 2013 Mar;10 (1) :52-8.|[3]Yates YJ, et al. The effect of tirofiban on microvascular thrombosis: crush model. Plast Reconstr Surg. 2005 Jul;116 (1) :205-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Am J Respir Cell Mol Biol. 2025 Feb 28.|bioRxiv. 2025 February 01.|Mol Divers. 2024 Dec 8.|Front Pharmacol. 2021 Oct 8:12:734603.

Alternative Products

CatalogName
FT142225-01Tirofiban
RM-T180699-01Tirofiban Impurity 99; Tirofiban Impurity W
RM-T180600-01Tirofiban Hcl
RM-T180627-01(R) -Tirofiban

Popular Products