USP22 Antibody - middle region

• Gene Name:

  Ubiquitin specific peptidase 22

• Gene Aliases:

  USP3L

• Gene ID:

  23326

• Swiss Prot:

  Q9UPT9

• Accession Number:

  NP_056091

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human USP22

• Target:

  USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.

• Partner Proteins:

  UBC; AASDHPPT; STAT3; TAF10; TADA2A; ATXN7; MYC; KAT2A; TRRAP; TAF9B; HIST1H2BD; TADA3; SUMO1; NFATC2; SIRT1; ATXN7L3; FUBP1; HIST2H2BE; HIST2H2AC; MRPL44; ATXN7L3B; USP27X; KIF7; KLHL23; ATXN7L2; TADA1; CCDC101; TADA2B; ENY2; SUPT20H; TAF5L; SND1; CNOT10

• Clonality:

  Polyclonal

• Type:

  Polyclonal Antibody

• Sequence:

  PSSCLVCEMSSLFQEFYSGHRSPHIPYKLLHLVWTHARHLAGYEQQDAHE

• Applications:

  WB

• Purification:

  Affinity Purified

• Assay Protocol:

  Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Reconstitution:

  For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

• Molecular Weight:

  60kDa

• Protein Length:

  525

• NCBI Gene Symbol:

  USP22

• Host or Source:

  Rabbit

• Protein Name:

  Ubiquitin carboxyl-terminal hydrolase 22

• Gene Name URL:

  USP22

• CAS Number:

  9007-83-4

• Nucleotide Accession Number:

  NM_015276