DAG peptide

• UNSPSC Description:

  DAG peptide is a cyclic peptide. DAG peptide selectively recognizes a subset of astrocytes that are activated in Alzheimer's disease (AD) starting at an early stage of the disease. DAG peptide can be used as a tool to enhance the delivery of therapeutics and imaging agents to sites of vascular changes and astrogliosis in diseases associated with neuroinflammation[1].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neurodegeneration

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/dag-peptide.html

• Purity:

  99.61

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C([C@@H](N)CSSC[C@H](NC1=O)C(O)=O)N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCCCN)=O)CCC(N)=O)=O)CCCCN)=O)CCCNC(N)=N)=O)=O)C)=O)CC(O)=O

• Molecular Weight:

  1006.16

• References & Citations:

  [1]Mann AP, et al. Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease. Nat Commun. 2017 Nov 10;8(1):1403.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported