Tesevatinib

• Target:

  VEGFR|||FLT|||EGFR|||Ephrin Receptor|||Src

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

• Purity:

  0.9866

• Bioactivity:

  Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor with IC50 values ??of 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4.

• Smiles:

  COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OC[C@H]1C[C@H]2CN(C)C[C@H]2C1

• Molecular Formula:

  C24H25Cl2FN4O2

• Molecular Weight:

  491.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  781613-23-8