BI-882370

• Target :

  Raf

• Related Pathways :

  MAPK

• Purity :

  0.9907

• Bioactivity :

  BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM) . BI-882370 also inhibits SRC family kinases.

• Smiles :

  CCCS(=O)(=O)Nc1ccc(F)c(c1F)-n1cc(-c2cncnc2)c2nc(ccc12)N(C)C1CCN(CC)CC1

• Molecular Formula :

  C28H33F2N7O2S

• Molecular Weight :

  569.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1392429-79-6