Apelin-36 (human)

• Target:

  Apelin receptor|||HIV Protease

• Related Pathways:

  Microbiology/Virology|||Proteases/Proteasome|||GPCR/G Protein

• Bioactivity:

  Endogenous APJ receptor agonist (EC50 = 20 nM) that is secreted by adipocytes. Binds with high affinity to human APJ receptors expressed in HEK 293 cells (pIC50= 8.61) . Involved in regulation of cardiovascular function, fluid homeostasis and feeding. Blocks entry of some HIV-1 and HIV-2 strains into NP-2/CD4 cells expressing APJ.

• Molecular Formula:

  C184H297N69O43S

• Molecular Weight:

  4195.87

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  252642-12-9