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Apelin-12

CAT: 0931-T39823Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T39823Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
229961-08-4
Target
Apelin receptor|||HIV Protease
Related Pathways
Microbiology/Virology|||GPCR/G Protein|||Proteases/Proteasome
Bioactivity
Apelin-12 is a highly potent C-terminal fragment of a polypeptide that exhibits a strong affinity towards the orphan receptor APJ. It plays a role in maintaining body fluid balance and regulating feeding control in the central nervous system. Additionally, Apelin-12 functions as an inhibitor of HIV-1 entry through the APJ receptor and demonstrates neuroprotective properties.
Smiles
CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Molecular Formula
C64H103N21O14S
Molecular Weight
1422.72
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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