Antisauvagine-30

CAT: 0931-TP2091Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-TP2091Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

220673-95-0

Target

CRFR

Related Pathways

GPCR/G Protein

Bioactivity

Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively) . Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells (pA2 = 8.49) . Prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo.

Molecular Formula

C161H274N48O46S

Molecular Weight

3650.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Antisauvagine-30

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