Antisauvagine-30

CAT: 0931-TP2091Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-TP2091Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
220673-95-0
Target
CRFR
Related Pathways
GPCR/G Protein
Bioactivity
Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2? and rat CRF1 receptors respectively) . Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2? cells (pA2 = 8.49) . Prevents stress-enhanced fear conditioning and MEK 1/2-dependent activation of ERK1/2 in mice in vivo.
Molecular Formula
C161H274N48O46S
Molecular Weight
3650.29
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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