ω-Conotoxin GVIA

• Target :

  Calcium Channel

• Related Pathways :

  Membrane transporter/Ion channel|||Metabolism

• Bioactivity :

  Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM) . Reduces (RS) -3,5-DHPG -induced long term depression in vivo.

• Smiles :

  O=C1[C@]2(N(C(=O)[C@H](CC(N)=O)NC(=O)[C@]3(NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@]4(NC(=O)C(NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC5=CC=C(O)C=C5)NC(=O)[C@H](CO)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@]6(N(C(=O)[C@H](CO)NC(=O)C(CSSC3)(NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@]7(N(C(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CSSC4)C[C@H](O)C7)[H])[H])C[C@H](O)C6)[H])[H])(CSSC[C@@H](C(N[C@@H](CC8=CC=C(O)C=C8)C(N)=O)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CC9=CC=C(O)C=C9)N1)[H])[H])[H])[H])C[C@H](O)C2)[H]

• Molecular Formula :

  C120H182N38O43S6

• Molecular Weight :

  3037

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  106375-28-4