α-Conotoxin AuIB

• Target:

  AChR

• Related Pathways:

  Neuroscience

• Bioactivity:

  Selective antagonist of ?3?4 nicotinic acetylcholine receptors. Displays > 100-fold selectivity over other receptor subunit combinations including ?2?2, ?2?4, ?3?2, ?4?2, ?4?4 and ?1?1??.

• Smiles:

  O=C1[C@]2(N(C(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](CO)NC(=O)[C@]4(NC(=O)[C@@H](NC(CN)=O)CSSC[C@](NC(=O)[C@]5(N1CCC5)[H])(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@@H](C)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CC(N)=O)C(=O)N7[C@](C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(N)=O)CSSC4)(CCC7)[H])[H])[H])[H])CCC2)[H]

• Molecular Formula:

  C65H89N17O21S4

• Molecular Weight:

  1572.76

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  216299-21-7