Conantokin G

CAT: 0931-MF-0045734Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0045734Size:5 mg
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CAS Number
93438-65-4
Target
IGluR
Related Pathways
Membrane transporter/Ion channel|||Neuroscience
Bioactivity
GluN2B (formally NR2B) selective, competitive antagonist of the NMDA receptor. Blocks NMDA-evoked current in mouse cortical neurons (IC50 = 480 nM) ; also inhibits NMDA-evoked responses in oocytes expressing GluN2B (formally NR2B), but not GluN2A (formally NR2A), subunits (IC50 ~300 nM) . Exhibits neuroprotective properties in vivo and in vitro.
Smiles
[C@@H](NC([C@@H](NC([C@@H](NC(CN)=O)CCC(O)=O)=O)CC(C(O)=O)C(O)=O)=O)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(N)=O)C(N)=O)=O)CO)=O)CCCCN)=O)CC(C(O)=O)C(O)=O)=O)CCCNC(=N)N)=O)[C@H](CC)C)=O)CC(C)C)=O)CC(C(O)=O)C(O)=O)=O)CCC(N)=O)=O)CC(N)=O)=O)CC(C(O)=O)C(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C(O)=O)C(O)=O
Molecular Formula
C88H138N26O44
Molecular Weight
2264.21
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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