CTOP

• Target:

  Opioid Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity:

  Potent and selective ? opioid receptor antagonist (Ki values are 0.96 and >10,000 nM for ? and ? receptors respectively) . Causes behavioral effects on central administration in vivo. Also increases K+ currents in rat locus ceruleus neurons in vitro via a ? receptor independent mechanism.

• Smiles:

  C (C=1C=2C (NC1) =CC=CC2) [C@H]3NC (=O) [C@H] (CC4=CC=C (O) C=C4) NC (=O) [C@@H] (NC ([C@@H] (CC5=CC=CC=C5) N) =O) CSSC (C) (C) [C@@H] (C (N[C@@H] ([C@@H] (C) O) C (N) =O) =O) NC (=O) [C@] ([C@@H] (C) O) (NC (=O) [C@H] (CCCN) NC3=O) [H]

• Molecular Formula:

  C50H67N11O11S2

• Molecular Weight:

  1062.28

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  103429-31-8