CRF (6-33) (human)

• Target:

  CRFR

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  CRF (6-33) (human) is a peptide inhibitor of corticotropin-releasing factor binding protein (CRFBP) that displaces CRF from CRFBP, suppresses body weight gain, and increases motor activity in obese rats in vivo.

• Smiles:

  [C@@H](CC1=CN=CN1)(NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@H](CC)C)N)=O)CO)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)[C@@H](C)O)=O)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(O)=O)CO)=O)=O)C)=O)CCC(N)=O)=O)CCC(N)=O)=O)C)=O)CC(C)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)C)=O)CCCNC(=N)N)=O)C)=O)CCSC)=O)CCC(O)=O)=O)CC(C)C)=O)C(C)C)=O)CCC(O)=O)=O)CCCNC(=N)N)=O)CC(C)C)=O)CC(C)C)=O

• Molecular Formula:

  C141H231N41O43S

• Molecular Weight:

  3220.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  120066-38-8