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Mambalgin 1

CAT: 0931-TP2003Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2003Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1609937-15-6
Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively) . Binds to closed/inactive channel. Selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Increases latency of withdrawal response in mouse tail-flick and paw-flick tests. Analgesic.
Molecular Formula
C272H429N85O84S10
Molecular Weight
6554.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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