PKC ? pseudosubstrate

• Target:

  PKC

• Related Pathways:

  Chromatin/Epigenetic|||Cytoskeletal Signaling

• Bioactivity:

  Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 ?M) . Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide.

• Molecular Formula:

  C177H294N62O38S3

• Molecular Weight:

  3994.84

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  172308-76-8