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CAT: 0931-MF-0097353Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0097353Size:1 mg
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CAS Number
863987-12-6
Target
PKC
Related Pathways
Chromatin/Epigenetic|||Cytoskeletal Signaling
Bioactivity
Novel, cell-permeable inhibitor of protein kinase M? (PKM?), a constitutively active, atypical PKC isozyme involved in LTP maintenance. Selectively blocks PKM?-induced synaptic potentiation in hippocampal slices in vitro. Reverses late-phase LTP (IC50 = 1 - 2.5 ?M) and produces persistent loss of 1-day-old spatial memory following central administration in vivo.
Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)CCCCN)=O)CCCNC(=N)N)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC(CCCCCCCCCCCCC)=O)CO)=O)[C@H](CC)C)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)C)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)C=2C=3C(NC2)=CC=CC3
Molecular Formula
C90H154N30O17
Molecular Weight
1928.4
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS6235920-01TSPAN8 (Tetraspanin-8, Tspan-8, Transmembrane 4 Superfamily Member 3, TM4SF3, Tumor-associated Antigen CO-029) (MaxLight 750)
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MBS6247488-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (AP)
MBS6249514-01CD151 (CD151 Antigen, CD151 Molecule, GP27, Membrane Glycoprotein SFA1, MER2, Platelet Endothelial Tetraspan Antigen 3, PETA 3, PETA-3, RAPH, SFA 1, SFA1, SFA-1, Tetraspanin-24, TSPAN-24) (FITC)
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