BAM (8-22)

• CAS Number :

  412961-36-5

• Target :

  MRGPR

• Related Pathways :

  GPCR/G Protein

• Bioactivity :

  Endogenous peptide fragment that is a potent agonist for MRGPRX1 (EC50 values are 8 - 150 nM) ; first isolated from bovine adrenal medulla. Unlike BAM 22P , does not contain the met-enkephalin motif therefore displays no affinity for opioid receptors.

• Smiles :

  C([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(NCC(O)=O)=O)=O)CCCNC(=N)N)=O)CCCCN)=O)CCC(N)=O)=O)=O)CC(O)=O)=O)CCSC)=O)=O)NC([C@@H](NC(=O)[C@H]5N(C([C@@H](NC(CNC([C@H](C(C)C)N)=O)=O)CCCNC(=N)N)=O)CCC5)CCC(O)=O)=O)C=6C=7C(NC6)=CC=CC7

• Molecular Formula :

  C91H127N25O23S

• Molecular Weight :

  1971.22

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C